Agenda
Updates in Stroke Prevention: Novel Diagnostics, Devices, Drugs
*The program is preliminary and could be subject to changes
7:00 – 8:00 am
FULL BREAKFAST PROVIDED
North Ballroom
8:00 – 8:15 am
MISSION, GOALS AND OBJECTIVES OF RAISE II
South Ballroom
RAISE Chairpersons: M. Edip Gurol (Neurology, MGH/HMS)
Marc Fisher (Neurology, BIDMC/HMS)
8:15 – 10:05 am
SESSION 1: NOVEL DIAGNOSTICS AND THE USE OF AI IN STROKE PREVENTION
South Ballroom
Co-Chairs: Dawn Kleindorfer (Neurology, U. Michigan), Cheryl Bushnell (Neurology, Wake Forest)
8:15–8:27: Using 12-leads EKG to Predict Afib and Other Conditions
Paul Friedman (Cardiology, Mayo Clinic, Rochester, MN)
8:27 – 8:39 Wearables for Stroke Prevention Research
Michael Gibson (Cardiology, BIDMC)
8:39 – 8:51 Long-term monitoring for AFib Detection
Tina Baykaner (Cardiology, Stanford)
8:51 – 9: 03 AI and Big Data in Stroke Prevention Research
Nassir Marrouche (Cardiac EP, Tulane Univ.)
09:03 – 09:15 Advances in Cardiac Imaging
Evin Yucel (Cardiology, MGH)
09:15 – 10:05 Discussion
Guven Guzeldere (Independent scholar), Karl Helmer (MGH/HMS), Jane Chen (Boston Scientific), Grant Neitzell (Medtronic)
10:05 – 10:25 am
BREAK
North Ballroom
10:25 am– 12:15 pm
SESSION 2: PREVENTION OF ISCHEMIC AND HEMORRHAGIC STROKES IN ATRIAL FIBRILLATION
South Ballroom
Co-Chairs: Magdy Selim (Neurology, Harvard Medical School), Clinton Wright (NINDS)
10:25 – 10:37 Factor XIa inhibitors in AFib
Carolyn Lam (Cardiology, Duke-NUS)
10:37 – 10: 49 Updates in Left Atrial Appendage Closure for Stroke Prevention in AFib
Vivek Reddy (Cardiac EP, NYC, NY)
10:49 – 11:01 Atrial Fibrillation Ablation and Stroke Risk
Vivek Reddy (Cardiac EP, NYC, NY)
11:01 – 11:13 Atrial Fibrillation and Cognitive Impairment
Rebecca Gottesman (NINDS)
11:13 – 11:25 Incorporating Advances in AFib Treatment into Clinical Practice: Challenges and Opportunities
M. Edip Gurol (MGH/HMS, Boston, MA)
11:25 – 12:15 Discussion
Mirko de Melis (Medtronic), Sydney Gaynor (AtriCure)
12:15 – 1:15 pm
LUNCH
North Ballroom
1:15 – 3:05 pm
SESSION 3: NEW DRUGS FOR STROKE PREVENTION
South Ballroom
Chairs: Argye Hillis (Neurology, JHU), Michelle Johansen (Neurology, JHU)
1:15 – 1:27 P2Y12 inhibitors: When to Use? What Other Data Do We Need?
Greg Albers (Neurology, Stanford)
1:27 – 1:39 GLP-1 Receptor Agonists and SGLT-2 Inhibitors for Stroke Prevention
Eda Cengiz (Endocrinology, UCSF)
1:39 – 1: 51 All ESUS / Atrial Cardiopathy Studies Failed: Now What?
Mitch Elkind (AHA)
1:51 – 2: 03 Updates on Management of Hyperlipidemia for Stroke Prevention
Seemant Chaturvedi (Neurology, University of Maryland)
2:03 – 2:15 Early Feasibility Study and Breakthrough Devices Programs: FDA Update
Andrew Farb (FDA)
2:15 – 3:05 Discussion
Hooman Kamel (Neurology, Cornell), Luciano Sposato (University of Western Ontario), Haitham Alabsi (J&J), Sara Hegab (Bayer), Maria Borentain (Bayer)
3:05 – 3:20 pm
BREAK
North Ballroom
3:20 – 5:10 pm
SESSION 4: NOVEL DEVICES FOR STROKE PREVENTION
South Ballroom
Co-Chairs: Lauren Sansing (Neurology, Yale) , Scott Janis (NINDS)
3:20 – 3: 32 New/Potential Studies in PFO Closure
Jeff Saver (Neurology, UCLA)
3:32 – 3:44 Renal Denervation for Hypertension Control
Naomi Fisher (Endocrinology, BWH, Boston, MA)
3:44 – 3:56 Prophylactic Ablation and LAA Obliteration During Major Cardiac Surgery
DJ Lakkireddy (Cardiac EP, Kansas City)
3:56 – 4:08 Combining LAAC and OAC for high embolic risk AF
Jeff Healey (PHRI/McMasters, CA)
4:08 – 4:35 Special Lecture: FDA-approval process for drugs and devices: progress and challenges
Robert M. Califf (United States Commissioner of Food and Drugs)
4:35 – 5:10 Discussion
David Wang (Barrow Neurological Institute), Gary Erzberger (Abbott), ), Yashasvi Sharma (AtriCure), Ed Kopesky (Boston Scientific)
6:30 – 9:30 pm
EVENING OF NETWORKING: BUILDING CONNECTIONS AND OPPORTUNITIES FOLLOWED BY SPECIAL PRESENTATION
Galaxy Ballroom
Joseph Broderick (Univ. Cincinnati) – GAINS website for Clinical Trials
7:00 – 8:00 am
FULL BREAKFAST PROVIDED
North Ballroom
8:00 – 10:30 am
WORKSHOPS TO DEVELOP CONSENSUS RECOMMENDATIONS
Participants are divided into three groups – each to develop recommendations.
Cavalier A Hall
Workshop 1: Novel Approaches to Stroke Prevention in Atrial Fibrillation
Moderators: Alvin Das (Neurology, BI/HMS, Boston), Shadi Yaghi (Neurology, Brown, RI), Andrea Russo (Cardiac EP, Cooper Univ)
Cavalier B Hall
Workshop 2: New Drugs for Non-AFib Stroke Prevention
Moderators: Baris Alten (Neurology, MGH/HMS, Boston), John Eikelboom (PHRI/McMasters, CA), Pooja Khatri (Neurology, University of Cincinnati)
Cavalier C Hall
Workshop 3: Updates on Devices/Interventions for Non-AFib Stroke Prevention
Moderators: Nicole Sur (U. Miami Neurology), Scott Kasner (Neurology, University of Pennsylvania), Seemant Chaturvedi (Neurology, University of Maryland)
10:30 – 10:45 am
BREAK
North Ballroom
10:45 am – 12:00 pm
WORKSHOP CHAIRS PRESENT RECOMMENDATIONS TO FULL ASSEMBLY
South Ballroom
Drafting of consensus statement is initiated – Chaired by M. Edip Gurol (MGH/HMS)
12:00 – 12:15 pm
CLOSING COMMENTS AND ADJOURNMENT