Agenda

Updates in Stroke Prevention: Novel Diagnostics, Devices, Drugs

*The program is preliminary and could be subject to changes

  7:00 – 8:00 am

FULL BREAKFAST PROVIDED

North Ballroom

  8:00 – 8:15 am

MISSION, GOALS AND OBJECTIVES OF RAISE II

South Ballroom

RAISE Chairpersons: M. Edip Gurol (Neurology, MGH/HMS)
Marc Fisher (Neurology, BIDMC/HMS)

  8:15 – 10:05 am

SESSION 1: NOVEL DIAGNOSTICS AND THE USE OF AI IN STROKE PREVENTION 

South Ballroom

Co-Chairs: Dawn Kleindorfer (Neurology, U. Michigan), Cheryl Bushnell (Neurology, Wake Forest)

8:15–8:27: Using 12-leads EKG to Predict Afib and Other Conditions
Paul Friedman (Cardiology, Mayo Clinic, Rochester, MN)

8:27 – 8:39 Wearables for Stroke Prevention Research
Michael Gibson (Cardiology, BIDMC)

8:39 – 8:51 Long-term monitoring for AFib Detection
Tina Baykaner (Cardiology, Stanford)

8:51 – 9: 03 AI and Big Data in Stroke Prevention Research
Nassir Marrouche (Cardiac EP, Tulane Univ.)

09:03 – 09:15 Advances in Cardiac Imaging
Evin Yucel (Cardiology, MGH)

09:15 – 10:05 Discussion
Guven Guzeldere (Independent scholar), Karl Helmer (MGH/HMS), Jane Chen (Boston Scientific), Grant Neitzell (Medtronic)

  10:05 – 10:25 am

BREAK

North Ballroom

  10:25 am– 12:15 pm

SESSION 2: PREVENTION OF ISCHEMIC AND HEMORRHAGIC STROKES IN ATRIAL FIBRILLATION

South Ballroom

Co-Chairs: Magdy Selim (Neurology, Harvard Medical School), Clinton Wright (NINDS)

10:25 – 10:37 Factor XIa inhibitors in AFib
Carolyn Lam (Cardiology, Duke-NUS)

10:37 – 10: 49 Updates in Left Atrial Appendage Closure for Stroke Prevention in AFib
Vivek Reddy (Cardiac EP, NYC, NY)

10:49 – 11:01 Atrial Fibrillation Ablation and Stroke Risk
Vivek Reddy (Cardiac EP, NYC, NY)

11:01 – 11:13 Atrial Fibrillation and Cognitive Impairment 
Rebecca Gottesman (NINDS)

11:13 – 11:25 Incorporating Advances in AFib Treatment into Clinical Practice: Challenges and Opportunities
M. Edip Gurol (MGH/HMS, Boston, MA)

11:25 – 12:15 Discussion
Mirko de Melis (Medtronic), Sydney Gaynor (AtriCure)

 

  12:15 – 1:15 pm

LUNCH

North Ballroom

  1:15 – 3:05 pm

SESSION 3: NEW DRUGS FOR STROKE PREVENTION

South Ballroom

Chairs:  Argye Hillis (Neurology, JHU), Michelle Johansen (Neurology, JHU)

1:15 – 1:27 P2Y12 inhibitors: When to Use? What Other Data Do We Need?
Greg Albers (Neurology, Stanford)

1:27 – 1:39 GLP-1 Receptor Agonists and SGLT-2 Inhibitors for Stroke Prevention
Eda Cengiz (Endocrinology, UCSF)

1:39 – 1: 51 All ESUS / Atrial Cardiopathy Studies Failed: Now What?

Mitch Elkind (AHA)

1:51 – 2: 03 Updates on Management of Hyperlipidemia for Stroke Prevention
Seemant Chaturvedi (Neurology, University of Maryland)

2:03 – 2:15 Early Feasibility Study and Breakthrough Devices Programs: FDA Update
Andrew Farb
(FDA)

2:15 – 3:05 Discussion
Hooman Kamel (Neurology, Cornell), Luciano Sposato (University of Western Ontario), Haitham Alabsi (J&J), Sara Hegab (Bayer), Maria Borentain (Bayer)

  3:05 – 3:20 pm

BREAK

North Ballroom

  3:20 – 5:10 pm

SESSION 4: NOVEL DEVICES FOR STROKE PREVENTION

South Ballroom

Co-Chairs:  Lauren Sansing (Neurology, Yale) , Scott Janis (NINDS)

3:20 – 3: 32 New/Potential Studies in PFO Closure
Jeff Saver (Neurology, UCLA)

3:32 – 3:44 Renal Denervation for Hypertension Control
Naomi Fisher (Endocrinology, BWH, Boston, MA)

3:44 – 3:56 Prophylactic Ablation and LAA Obliteration During Major Cardiac Surgery
DJ Lakkireddy (Cardiac EP, Kansas City)

3:56 – 4:08 Combining LAAC and OAC for high embolic risk AF
Jeff Healey (PHRI/McMasters, CA)

4:08 – 4:35 Special LectureFDA-approval process for drugs and devices: progress and challenges
Robert M. Califf
(United States Commissioner of Food and Drugs)

4:35 – 5:10 Discussion
David Wang (Barrow Neurological Institute), Gary Erzberger (Abbott), ), Yashasvi Sharma (AtriCure), Ed Kopesky (Boston Scientific)

  6:30 – 9:30 pm

EVENING OF NETWORKING: BUILDING CONNECTIONS AND OPPORTUNITIES FOLLOWED BY SPECIAL PRESENTATION

Galaxy Ballroom

Joseph Broderick (Univ. Cincinnati) – GAINS website for Clinical Trials

  7:00 – 8:00 am

FULL BREAKFAST PROVIDED

North Ballroom

  8:00 – 10:30 am

WORKSHOPS TO DEVELOP CONSENSUS RECOMMENDATIONS

Participants are divided into three groups – each to develop recommendations.

Cavalier A Hall
Workshop 1:  Novel Approaches to Stroke Prevention in Atrial Fibrillation

Moderators: Alvin Das (Neurology, BI/HMS, Boston), Shadi Yaghi (Neurology, Brown, RI), Andrea Russo (Cardiac EP, Cooper Univ)

Cavalier B Hall
Workshop 2: New Drugs for Non-AFib Stroke Prevention
Moderators:
Baris Alten (Neurology, MGH/HMS, Boston), John Eikelboom (PHRI/McMasters, CA), Pooja Khatri (Neurology, University of Cincinnati)

Cavalier C Hall
Workshop 3: Updates on Devices/Interventions for Non-AFib Stroke Prevention

Moderators: Nicole Sur (U. Miami Neurology), Scott Kasner (Neurology, University of Pennsylvania), Seemant Chaturvedi (Neurology, University of Maryland)

  10:30 – 10:45 am

BREAK

North Ballroom

  10:45 am – 12:00 pm

WORKSHOP CHAIRS PRESENT RECOMMENDATIONS TO FULL ASSEMBLY

South Ballroom

Drafting of consensus statement is initiated – Chaired by M. Edip Gurol (MGH/HMS)

  12:00 – 12:15 pm

CLOSING COMMENTS AND ADJOURNMENT